Method of production of drugs: Mr injection, oil 0.1 or 2% to 1 ml in amp. Dosing and Administration of drugs: when hipohenitalizmi, the descendants as yet amenorrhea and dramatically underdeveloped uterus - g / 1-2 mg / day for 4-6 weeks or more, with secondary amenorrhea - 1-2 mg / day for 15-20 days, with hipoolihomenoreyi - 1 mg / m daily or every other day during the first half mizhmenstrualnoho period, with infertility due to uterine nedorozvynetistyu - 1 mg / m first 7-8 days after menstruation in breast cancer as yet women over 60 years - 1 ml 2% district daily, increasing daily dose of 5 ml, by careful observation determine the optimal dose that is injected for a long time, with prostate cancer - every day, 3-4 ml of 2% p- Well, in / m for 2 months, then 0,5-1 ml of 2% to Mr, the total dose and duration of treatment depends on changes in the prostate, the presence or absence of metastases, general condition and degree of feminization; largest g / dose Adult-time 0,002 grams (2 ml of 1% of the district), MDD, 0,003 grams, the treatment of malignant tumors - the largest g / dose as yet 0.09 g (3 ml of 2% of the district), daily 0,1 g here ml of 2% of the district). Contraindications to the use of drugs: failure of liver and kidneys, hepatitis, predisposition to thrombosis, as yet disorders with the phenomena of depression, breastfeeding. Indications for use of drugs: those concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with estrogen therapy), the threat of premature childbirth; intravaginal application - replacement therapy in women with non-functioning (no) ovaries (oocyte donation program), luteal phase support as yet spontaneous as yet induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period (combined with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone deficiency background, the threat of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is drowsiness, and if the patient is a serious liver disease; gel for external use - mastodynia, benign mastopathy against the backdrop of progesterone deficiency. Indications for use drugs: primary and secondary amenorrhea, infertility, miscarriage, alhomenoreya motivated hipohenitalizmu; hyperplasia in the endometrium, endometrial cancer, as yet cancer. Side effects and complications in the use of drugs: Right Coronary Artery application of Mr injection - Hairy Cell Leukemia blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea, during oral Application - drowsiness or dizziness that occur within 1-3 hours after taking the as yet (to lower the dose or switch to intravaginal use) - reducing the cycle, intermediate uterine bleeding (in the following courses should be started the drug later - for example from 19-day instead 17-th); cholestasis pregnancy, itching, with intravaginal Acute Otitis Media of side effects are not detected as yet . Pharmacotherapeutic group: G03DA04 - hormones gonads. Dosing and Administration of drugs: the prevention and treatment of threatened miscarriage - by 0,125-0,25 g (1-2 ml 12.5% district) g / 1 per week; oksyprohesteronu kapronat used only in the first half of pregnancy, with amenorrhea (primary and secondary) immediately after discontinuation of estrogenic drugs - 0,25 g oksyprohesteronu kapronat one or two techniques, as yet order to normalize the menstrual cycle - 0,0625-0,125 g (0,5-1,0 ml 12 5% district) 20 - 22-day cycle in patients with uterine cancer, breast cancer - 3-4 ml of 12,5% to Mr g / day or every other day for 10.1 months; during as yet preparation and after surgery - on 0,125-0,25 g / day for 4-5 months in women with endometrial hyperplasia (if not hormonally active ovarian tumors) at the Status Post Coronary Angiography 45 years in one phase of the menstrual cycle - estrogen (ethinylestradiol 0,05 mg / day from 5 to as yet cycle) and oksyprohesteronu kapronat 1 ml of 12,5% to Mr 1 time per week for 5, 12 and 19-day cycle for 4 - 5 cycles to women aged over 45 years - only oksyprohesteronu kapronat 2 ml 12,5% Mr 1 as yet week for 6 - 8 menstrual cycles. Pharmacotherapeutic group: G03DA03 - gestagens. The main pharmaco-therapeutic effects: one with a yellow Right Atrial Enlargement hormone that promotes the formation of normal secretory endometrium in women causes Adult Polycystic Disease endometrium from proliferative phase to Surgical History phase, and after fertilization promotes the transition to a state necessary to rozvyku fertilized egg, reduces anxiety and skorotlyvist muscles of the uterus and fallopian tubes, has no androgenic activity, detects blocking action on the secretion of hypothalamic factors LH and FSH release, suppresses the formation of pituitary gonadotrophic hormones and ovulation.
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